BMRB Entry 4595
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR4595
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
NMR-STAR v2.1 text file (deprecated)
XML gzip file.
RDF gzip file.
All files associated with the entry
Title: Cystic fibrosis transmembrane conductance regulator: solution structures of peptides based on the Phe508 region, the most common site of disease-causing DeltaF508 mutation -- P25 PubMed: 10360942
Deposition date: 2000-05-05 Original release date: 2000-12-04
Authors: Massiah, M.; Ko, Y.; Pedersen, P.; Mildvan, A.
Citation: Massiah, M.; Ko, Y.; Pedersen, P.; Mildvan, A.. "Cystic fibrosis transmembrane conductance regulator: solution structures of peptides based on the Phe508 region, the most common site of disease-causing DeltaF508 mutation" Biochemistry 38, 7453-7461 (1999).
Assembly members:
protein (cystic fibrosis transmembrane conductance regulator (CFTR)), polymer, 25 residues, Formula weight is not available
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eucaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: chemical synthesis
Entity Sequences (FASTA):
protein (cystic fibrosis transmembrane conductance regulator (CFTR)): MPGTIKENIIGVSYDEYRYR
SVIKA
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 155 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | cystic fibrosis transmembrane conductance regulator (CFTR) | 1 |
Entities:
Entity 1, cystic fibrosis transmembrane conductance regulator (CFTR) 25 residues - Formula weight is not available
| 1 | MET | PRO | GLY | THR | ILE | LYS | GLU | ASN | ILE | ILE | ||||
| 2 | GLY | VAL | SER | TYR | ASP | GLU | TYR | ARG | TYR | ARG | ||||
| 3 | SER | VAL | ILE | LYS | ALA |
Samples:
sample_1: protein (cystic fibrosis transmembrane conductance regulator (CFTR)) 1.4 mM; Trifluroethanol 43%
sample_cond_1: pH: 4.0; temperature: 298 K; pressure: 1 atm
Experiments:
| Name | Sample | Sample state | Sample conditions |
|---|---|---|---|
| NOESY | sample_1 | not available | sample_cond_1 |
| COSY | sample_1 | not available | sample_cond_1 |
| TOCSY | sample_1 | not available | sample_cond_1 |
Software:
X-PLOR v3.8 - structure refinement
NMRVIEW2.1 - Structure solution
NMR spectrometers:
- Varian UnityPlus 600 MHz